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Split-design approach enhances the therapeutic efficacy of ligand-based CAR-T cells against multiple B-cell malignancies
Authors: Shuhong Li , Licai Shi , Lijun Zhao , Qiaoru Guo , Jun Li , Ze-Lin Liu , Zhi Guo , Yu J Cao
Journal: Nat Commun
PubMed ID: 39528513
Doi: 10.1038/s41467-024-54150-z
Products & Services: Recombinant Proteins   Gene Synthesis   
The TMEM132B-GABAA receptor complex controls alcohol actions in the brain
Authors: Guohao Wang , Shixiao Peng , Miriam Reyes Mendez , Angelo Keramidas , David Castellano , Kunwei Wu , Wenyan Han , Qingjun Tian , Lijin Dong , Yan Li , Wei Lu
Journal: Cell
PubMed ID: 39357522
Doi: 10.1016/j.cell.2024.09.006
Products & Services: Polyclonal Antibody Services   
Interactions established by isoform-specific TrkB-T1 sequences govern inflammatory response and neurotoxicity in stroke
Authors: Lola Ugalde-Triviño, Gonzalo S. Tejeda, Gema M. Esteban-Ortega, Margarita Díaz-Guerra
Journal: bioRxiv
Doi: doi.org/10.1101/2024.11.13.623346
Products & Services: Catalog Peptides   
Both chebulagic acid and punicalagin inhibit respiratory syncytial virus entry via multi-targeting glycoprotein and fusion protein
Authors: Yingcai Xiong , Keyu Tao , Tao Li , Yinghui Zhou , Zhaowei Zhang , Weiying Ou , Zhao Wang , Shouchuan Wang , Yayi Hou , Peng Cao , Jianjian Ji
Journal: J Virol
PubMed ID: 39508604
Doi: 10.1128/jvi.01536-24
Products & Services: Peptoid Synthesis   
Engineered mRNAs with stable structures minimize double-stranded RNA formation and increase protein expression
Authors: Qianshan Qin , Huayuan Yan , Weixiang Gao , Ruyin Cao , Guopeng Liu , Xiaojing Zhang , Niangang Wang , Wenjie Zuo , Lei Yuan , Peng Gao , Qi Liu
Journal: J Mol Biol
PubMed ID: 39427983
Doi: 10.1016/J.JMB.2024.168822
Products & Services: Gene Synthesis   
Spatial organization of PI3K-PI(3,4,5)P3-AKT signaling by focal adhesions
Authors: Jing Wang , Zhengyang An , Zhongsheng Wu , Wei Zhou , Pengyu Sun , Piyu Wu , Song Dang , Rui Xue , Xue Bai , Yongtao Du , Rongmei Chen , Wenxu Wang , Pei Huang , Sin Man Lam , Youwei Ai , Suling Liu , Guanghou Shui , Zhe Zhang , Zheng Liu , Jianyong Huang , Xiaohong Fang , Kangmin He
Journal: Mol Cell
PubMed ID: 39488211
Doi: 10.1016/j.molcel.2024.10.010
Products & Services: 5X Sample Buffer   
RAD18-catalysed formation of ubiquitination intermediate mimic of proliferating cell nuclear antigen PCNA
Authors: Liying Zhang, Zhiheng Deng, Yunxiang Du, Ziyu Xu, Tianyi Zhang, Zebin Tong, Huasong Ai, Lu-Jun Liang, Lei Liu
Journal: Bioorg Med Chem
PubMed ID: 39580855
Doi: 10.1016/j.bmc.2024.118016
Products & Services: Gene Synthesis   Proteins, Expression, Isolation and Analysis   
A high-performance protein preparation approach in a single column-free step
Authors: Yuan Huang, Yuanyuan Zhang, Xiaofeng Yang, Zhanglin Lin
Journal: Trends Biotechnol
PubMed ID: 39537535
Doi: 10.1016/j.tibtech.2024.10.008
Products & Services: Proteins, Expression, Isolation and Analysis   
SARS-CoV-2 N protein coordinates viral particle assembly through multiple domains
Authors: Yuewen Han 1, Haiwu Zhou 1, Cong Liu 1, Weiwei Wang 1, Yali Qin 2, Mingzhou Chen
Journal: Journal of Virology
PubMed ID: 39412257
Doi: 10.1128/jvi.01036-24
Products & Services: Plasmids for SARS-CoV-2 Detection and Research   Gene Synthesis   
Single-Dose Physically Cross-Linked Hyaluronic Acid and Lipid Hybrid Nanoparticles Containing Cyclic Guanosine Monophosphate-Adenosine Monophosphate Eliminate Established Tumors
Authors: Jinchao Yu , Xinyan Li , Junyao Li , Nan Sun , Peng Cheng , Jiayi Huang , Sai Li , Rui Kuai
Journal: ACS Nano
PubMed ID: 39418110
Doi: 10.1021/acsnano.4c10673
Products & Services: Recombinant Proteins