1mg/mL

CD19 is a transmembrane glycoprotein primarily expressed on B lymphocytes. It plays two major roles in human B cells: acting as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane and working within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways.

1mg/mL

The PEmax mRNA expresses an optimized prime editor enzymatic protein, which further increased editing efficiency in synergy with PE4, PE5 and engineered pegRNAs (Chen P, et al. 2021, Cell 184, 5635-5652). After efficient delivery into cells or animals, PEmax mRNA can translate into protein including a nickase and reverse transcriptase function for gene editing in cells.

1mg/mL

The mCherry mRNA expresses the fluorescent protein mCherry (recommended Ex: 560nm, recommended Em: 620nm), which is a DsRed protein found in Discosoma Sp. This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudoUridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA.

1mg/mL

Ovalbumin (OVA) is the major egg white protein, commonly used as an allergen and a model for serpin research. This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudoUridine for enhanced expression and reduced immunogenicity. The mRNA has a CD33 secretory peptide build in to help secreting the expressed protein, and a 100A tail in its sequence, mimics a mature mRNA.

1mg/mL

The saCas9 mRNA expresses an wild type Staphylococcus aureus cas9 enzymatic protein. This mRNA is capped with Cap1-AG structure with high capping efficiency. It has 100% substituted with N1-methylpseudouridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA. After efficient delivery, saCas9 mRNA can translate into protein function for gene editing in cells.

1mg/mL

tdTomato mRNA encodes for a red fluorescent protein derived from corals of the genus Discosoma. It displays excitation and emission maxima of 554 and 581 nm, respectively. tdTomato is optimized for cell and tissue imaging, with improved fluorescence intensity and stability.

1mg/mL

Spike protein of SARS-COV2 sequence has been identified during the pandemic. This Spike mRNA sequence is a synthetic construct HCV1145 Moderna (mRNA-1273) vaccine sequence.

1mg/mL  

The scarless eGFP circular RNA (circRNA) expresses an enhanced green fluorescent protein (Ex: 488nm, Em: 507nm). This circRNA is generated via PIE- Self circularization and does not have scar sequence. CVB3 IRES is designed in this circular RNA for initiating the IRES dependent ribosome recruiting and translation. All bases are non-modified. EGFP circRNA can be used as fluorescence reporter sequence in RNA therapeutics and delivery system development projects.

0.15mg/mL

The LNP formulation loaded with eGFP mRNA (m1Ψ) is prepared using generic LNP formulation with main ionizable lipid of SM102. The payload EGFP mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudoUridine. It expresses an enhanced green fluorescent protein (Ex: 488nm, Em: 507nm). This formulation is a good control for testing if SM102 LNP is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model.

0.15mg/mL

The LNP formulation loaded with eGFP mRNA (m1Ψ) is prepared using generic LNP formulation with main ionizable lipid of ALC0315. The payload EGFP mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudoUridine. It expresses an enhanced green fluorescent protein (Ex: 488nm, Em: 507nm). This formulation is a good control for testing if ALC0315 LNP is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model.

0.15mg/mL

The LNP formulation loaded with eGFP mRNA (5MOU) is prepared using generic LNP formulation with main ionizable lipid of SM102. The payload EGFP mRNA (5MOU) has all the U bases 100% modified with 5-methoxy Uridine. It expresses an enhanced green fluorescent protein (Ex: 488nm, Em: 507nm). This formulation is a good control for testing if SM102 LNP is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model.

0.15mg/mL

The LNP formulation loaded with eGFP mRNA (m1Ψ) is prepared using generic LNP formulation with main ionizable lipid of LP01. The payload EGFP mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudoUridine. It expresses an enhanced green fluorescent protein (Ex: 488nm, Em: 507nm). This formulation is a good control for testing if LP01 LNP is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model.