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Cynarin as a potent anti‑osteolytic agent: Targeting MAPK and Nrf2‑Keap1 pathways for osteoclast inhibition and bone protection

Authors: Rui Chao, Yexin Wang, Zhan Liu, Tianhao Wan, Yi Mao, Xinru Xie, Lei Sun, Weifeng Xu, Xuzhuo Chen, Shanyong Zhang

Journal: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

PubMed ID: PMC12488209

Doi: 10.3892/ijmm.2025.5647

Products & Services: Proteins, Expression, Isolation and Analysis

The EP300-Targeting Drug CCS1477 Inhibits the Growth and Development of Diffuse Large B-Cell Lymphoma by Promoting Apoptosis and Mitophagy to Reduce Drug Resistance

Authors: Rujia Si, Yihan Zhang, Bowen Hu, Yuxin Du, Dan Zou, Shaodi Wen, Xiaoyue Du, Xin Chen, Chen Peng, Shulei Fu, Shiying Zhu, Fan Du, Xiaofeng Sha, Ning Ding, Cong Xu, Bo Shen

Journal: Anti-Cancer Agents in Medicinal Chemistry

Doi: 10.2174/0118715206430859250915050817

Products & Services: Proteins, Expression, Isolation and Analysis

Activation of mechanosensitive ion channel Piezo1 linking metabolic reprogramming and pro-inflammatory responses in hepatocellular carcinoma

Authors: Juanfen Mo, YuXuan Zhang, Chenxi Cao, WeiLi Zheng, Li Zheng, Xiaoguang Wang, Shiyue Wang, Jiayuan Wu, Yi Bao

Journal: Cell Communication and Signaling

PubMed ID: 40514668

Doi: 10.1186/s12964-025-02289-7

Products & Services: Proteins, Expression, Isolation and Analysis

Potential role of TRAF2 in pulmonary hypertension in broiler chickens and preparation and specificity analysis of its polyclonal antibody

Authors: Wen Peng, Gen Wan, Sufang Cheng, Guyue Li, Liling Liu, Juan Chen, Pei Liu, Xiaoquan Guo, Xiaona Gao, Gaofeng Cai, Zhanhong Zheng, Ping Liu

Journal: Int J Biol Macromol

PubMed ID: 39798767

Doi: doi.org/10.1016/j.ijbiomac.2025.139741

Products & Services: Proteins, Expression, Isolation and Analysis

hypocretin-1/hypocretin receptor 1 regulates neuroplasticity and cognitive function through hippocampal lactate homeostasis in depressed model

Authors: Bing Chen , Kangyu Jin , Jingyi Dong , Shangping Cheng , Lingzhuo Kong , Shaohua Hu , Zuobing Chen, Jing Lu

Journal: Advanced Science

PubMed ID: 39119889

Doi: 10.1002/advs.202405354

Products & Services: Proteins, Expression, Isolation and Analysis eBlot ? L1 Fast Wet Transfer System

Reversible control of kinase signaling through chemical-induced dephosphorylation

Authors: Ying Sun , Rihong Zhou , Jin Hu , Shan Feng , Qi Hu

Journal: Communications Biology

PubMed ID: 39217250

Doi: 10.1038/s42003-024-06771-9

Products & Services: Proteins, Expression, Isolation and Analysis Recombinant Proteins

Blue light induced ferroptosis via STAT3/GPX4/SLC7A11/FTH1 in conjunctiva epithelium in vivo and in vitro

Authors: Qianjie Yang, Yutong Xia, Kuangqi Chen, Yinhao Wang, Dongjie Song, Jiru Zhu, Jianping Tong, Ye Shen

Journal: J Photochem Photobiol B

PubMed ID: 38663336

Doi: 10.1016/j.jphotobiol.2024.112908

Products & Services: Molecular Biology Reagents

The Transpeptidase Sortase A Binds Nucleic Acids and Mediates Mammalian Cell Labeling

Authors: Yingzheng Liu, Zhike Lu, Panfeng Wu, Zhaohui Liang, Zhenxing Yu, Ke Ni, Lijia Ma

Journal: Adv Sci (Weinh)

PubMed ID: 38581131

Doi: 10.1002/advs.202305605

Products & Services: Proteins, Expression, Isolation and Analysis

Guiding bar motif of thioredoxin reductase 1 modulates enzymatic activity and inhibitor binding by communicating with the co-factor FAD and regulating the flexible C-terminal redox motif

Authors: Wuyang Shi , Shibo Sun , Haowen Liu , Yao Meng , Kangshuai Ren , Guoying Wang , Minghui Liu , Jiaqi Wu , Yue Zhang , Huang Huang , Meiyun Shi , Weiping Xu , Qiang Ma , Bingbing Sun , Jianqiang Xu

Journal: Redox biology

Doi: 10.1016/j.redox.2024.103050

Products & Services: Proteins, Expression, Isolation and Analysis

Mechanosensitive accumulation of non-muscle myosin IIB during mitosis requires its translocation activity

Authors: Chao Wang , Jingjing Ding , Qiaodong Wei , Shoukang Du , Xiaobo Gong , Ting Gang Chew

Journal: iScience .

PubMed ID: 37720093

Doi: 10.1016/j.isci.2023.107773

Products & Services: Proteins, Expression, Isolation and Analysis

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