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Identification of the Shigella flexneri Wzy Domain Modulating Wzz_pHS-2 Interaction and Detection of the Wzy/Wzz/Oag Complex

Authors: Alice Ascari, Elizabeth Ngoc Hoa Tran, Bart A Eijkelkamp, Renato Morona

Journal: J Bacteriol

PubMed ID: 35980183

Doi: 10.1128/jb.00224-22

Products & Services: Proteins, Expression, Isolation and Analysis

Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains

Authors: Lining Lu, Xiaoguo Zhai, Xiaolong Li, Shuansuo Wang, Lijun Zhang, Luyang Wang, Xi Jin, Lujun Liang, Zhiheng Deng, Zichen Li, Yanfeng Wang, Xiangdong Fu, Honggang Hu, Jiawei Wang, Ziqing Mei, Zhengguo He, Feng Wang

Journal: Nat Commun

PubMed ID: 35945250

Doi: 10.1038/s41467-022-32364-3

Products & Services: Codon Optimization

ChAdOx1 nCoV-19 (AZD1222) or nCoV-19-Beta (AZD2816) protect Syrian hamsters against Beta Delta and Omicron variants

Authors: Neeltje van Doremalen, Jonathan E Schulz, Danielle R Adney, Taylor A Saturday, Robert J Fischer, Claude Kwe Yinda, Nazia Thakur, Joseph Newman, Marta Ulaszewska, Sandra Belij-Rammerstorfer, Greg Saturday, Alexandra J Spencer, Dalan Bailey, Colin A Russell, Sarah C Gilbert, Teresa Lambe, Vincent J Munster

Journal: Nat Commun

PubMed ID: 35941149

Doi: 10.1038/s41467-022-32248-6

Products & Services: Catalog Antibody

Generation of Human Domain Antibody Fragments as Potential Insecticidal Agents against by Cadherin-Based Screening

Authors: Xiaodan Hu, Xiao Zhang, Yuan Liu, Meijing Gao, Manman Lin, Yajing Xie, Qing Zhu, Chongxin Xu, Xianjin Liu, Dalene Vosloo, Ofentse Jacob Pooe

Journal: J Agric Food Chem

PubMed ID: 35944165

Doi: 10.1021/acs.jafc.2c02000

Products & Services: Molecular Biology Reagents

Dihydropyridine-derived calcium channel blocker as a promising anti-Hantaviral entry inhibitor

Authors: Bin Wang , Jiawei Pei, Hui Zhang , Jia Li , Yamei Dang , He Liu , Yuan Wang , Liang Zhang , Libin Qi , Yuewu Yang , Linfeng Cheng , Yangchao Dong , Airong Qian , Zhikai Xu , Yingfeng Lei , Fanglin Zhang , Wei Ye

Journal: Front Pharmacol .

PubMed ID: 36105208

Doi: 10.3389/fphar.2022.940178.

Products & Services: Gene Synthesis

Reduced sister chromatid cohesion acts as a tumor penetrance modifier

Authors: Jun Wang, Holly R Thomas, Yu Chen, Stefanie M Percival, Stephanie C Waldrep, Ryne C Ramaker, Robert G Thompson, Sara J Cooper, Zechen Chong, John M Parant

Journal: PLoS Genet

PubMed ID: 35994499

Doi: 10.1371/journal.pgen.1010341

Products & Services: Gene Synthesis

Novel Hits for N-Myristoyltransferase Inhibition Discovered by Docking-Based Screening

Authors: Danislav S Spassov, Mariyana Atanasova, Irini Doytchinova

Journal: Molecules

PubMed ID: 36080246

Doi: 10.3390/molecules27175478

Products & Services: Catalog Peptides

Structure and engineering of the minimal type VI CRISPR-Cas13bt3

Authors: Ryoya Nakagawa, Soumya Kannan, Han Altae-Tran, Satoru N Takeda, Atsuhiro Tomita, Hisato Hirano, Tsukasa Kusakizako, Tomohiro Nishizawa, Keitaro Yamashita, Feng Zhang, Hiroshi Nishimasu, Osamu Nureki

Journal: Mol Cell

PubMed ID: 36027912

Doi: 10.1016/j.molcel.2022.08.001

Products & Services: Synthetic sgRNA and crRNA Service

Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease

Authors: Annelies Stevaert, Ria Van Berwaer, Cato Mestdagh, Julie Vandeput, Els Vanstreels, Valerie Raeymaekers, Manon Laporte, Lieve Naesens

Journal: MBio

PubMed ID: 35913162

Doi: 10.1128/mbio.01376-22

Products & Services: Proteins, Expression, Isolation and Analysis

TCR extracellular domain genetically linked to CD28, 2B4/41BB and DAP10/CD3ζ -engineered NK cells mediates antitumor effects

Authors: Shance Li, Chaoting Zhang, Luyan Shen, Xia Teng, Yefei Xiao, Bentong Yu, Zheming Lu