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目录产品 » Periostin/OSF-2, His, Human
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Periostin/OSF-2, His, Human

Periostin is a matricellular protein that is expressed in several tissues during embryonic development; however, its expression in adults is mostly restricted to collagen-rich connective tissues. Periostin is expressed only briefly during kidney development, but it is not normally detected in the adult kidney. Recent evidence has revealed that periostin is aberrantly expressed in several forms of chronic kidney disease (CKD), and that its expression correlates with the degree of interstitial fibrosis and the decline in renal function.
￥3600
Z05748-100

产品简介
Species Human
Protein Construction
Periostin/OSF-2 (Asn22-Gln836)
Accession # Q15063		 His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 92.1 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 93-100 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles.
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图例
Periostin/OSF-2, His, Human

Immobilized Periostin/OSF-2, His, Human, His Tag at 1 μg /ml (100 μl/well) on the plate. Dose response curve for Anti-Periostin Antibody, hFc Tag with the EC50 of 7.7ng/ml determined by ELISA. »

Periostin/OSF-2, His, Human

The purity of Periostin/OSF-2, His, Human is greater than 95% as determined by SEC-HPLC. »

Periostin/OSF-2, His, Human

Periostin/OSF-2, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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技术背景
Target Background Periostin is a matricellular protein that is expressed in several tissues during embryonic development; however, its expression in adults is mostly restricted to collagen-rich connective tissues. Periostin is expressed only briefly during kidney development, but it is not normally detected in the adult kidney. Recent evidence has revealed that periostin is aberrantly expressed in several forms of chronic kidney disease (CKD), and that its expression correlates with the degree of interstitial fibrosis and the decline in renal function.
Synonyms Periostin; PN; OSF-2; POSTN; OSF2; Fasciclin I-like; PDLPOSTN; PNRP11-412K4.1; TRIF52
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.