MADCAM1 hFc Chimera, Human
| ¥3000 | |
| Z05623-100 | |
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| ¥3000 | |
| Z05623-100 | |
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| Species | Human | ||||
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 58.17 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 75-95 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Immobilized MADCAM1 hFc Chimera, Human, hFc Tag at 1 μg /ml(100 μl/well) on the plate. Dose response curve for Biotinylated Anti-MADCAM1 Antibody, hFc Tag with the EC50 of 16.6ng/ml determined by ELISA. »
Immobilized Human ITGA4&ITGB7, His Tag at 5 μg /ml (100 μl/well) on the plate. Dose response curve for MADCAM1 hFc Chimera, Human, hFc Tag with the EC50 of 5.5 μg /ml determined by ELISA. »
The purity of MADCAM1 hFc Chimera, Human is greater than 95% as determined by SEC-HPLC. »
MADCAM1 hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95% »
| Target Background | Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of our study was to determine whether selected single nucleotide polymorphisms (SNPs) of the MADCAM1 gene are associated with development of serious complications after aHSCT. |
| Synonyms | MAdCAM-1; MADCAM1; MACAM1 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.