| ￥4100 | |
| Z05333-100 | |
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| Species | Human | ||||
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1 EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 70.60 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 71-75 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl (pH 8.5). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
Immobilized GAS6, His, Human, His Tag at 5 μg/ml(100 μl/well) on the plate. Dose response curve for Human Axl, hFc Tag with the EC50 of 2.2ng/ml determined by ELISA. »
Immobilized Human MERTK, mFc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for GAS6, His, Human, His Tag with the EC50 of 2.14 μg/ml determined by ELISA. »
Immobilized GAS6, His, Human at 5 μg/ml(100 μl/well) on the plate. Dose response curve for Anti-GAS6 Antibody, hFc Tag with the EC50 of 13.2ng/ml determined by ELISA. »
The purity of GAS6, His, Human is greater than 90% as determined by SEC-HPLC. »
GAS6, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
GAS6, His, Human, His Tag immobilized on CM5 Chip can bind Human TYRO3, His Tag with an affinity constant of 2.36 μM as determined in SPR assay (Biacore T200). »
| Target Background | Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM). |
| Synonyms | GAS-6; AXLLG; GAS6; DKFZp666G247; FLJ34709 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
