| Species | Human | ||||
| Protein Construction |
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its esterase activity. Test result meets the standard. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 32.22 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
The purity of CA12/Carbonic anhydrase XII, His, Human is greater than 95% as determined by SEC-HPLC. »
CA12/Carbonic anhydrase XII, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
| Target Background | Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Carbonic anhydrase XII (CA XII) is a key mediator of several signaling pathways that are involved in cancer development. |
| Synonyms | Carbonic anhydrase; CA12; CAXII; Carbonic anhydrase 12; CA-XII; Tumor antigen HOM-RCC-3.1.3 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.