| ￥3300 | |
| Z03813-100 | |
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| Species | Human | ||||
| Protein Construction |
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| Purity | > 95% as determined by Bis-Tris PAGE | ||||
| Endotoxin Level | Less than 1 EU per μg by the LAL method. | ||||
| Biological Activity | Immobilized DLL3, His, Human (Cat.No.: Z03813) at 0.1 μg/ml can bind Anti-DLL3 Antibody. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 50.4 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, 200 mM Arginine, pH 7.4. | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the lyophilized product remains stable for 6 months at -20℃ or below as supplied from the date of receipt. -80℃ for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
DLL3, His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
Anti-DLL3 Antibody captured on CM5 Chip via Protein A can bind DLL3, His, Human with an affinity constant of 0.22 nM as determined in SPR assay (Biacore T200). »
Immobilized DLL3, His, Human at 0.1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 2.3 ng/ml determined by ELISA. »
| Target Background | DLL3, a transmembrane protein in the Delta/Serrate/Lag-2 (DSL) family of Notch ligands, inhibits primary neurogenesis and helps divert neurons along specific differentiation pathways. It also contributes to the formation of somite boundaries during paraxial mesoderm segmentation. |
| Synonyms | Delta3; DLL3; Pudgy; SCDO1; SCDO1delta3 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
