Neurogranin is a post synaptic protein that is expressed in dendritic cytoplasm. It modulates calcium-mediated signaling pathways and plays critical role in synaptic plasticity. Recently Neurogranin (48-76) was identified as a major neurogranin peptide fragment in human brain and it was found that patients with Alzheimer’s Disease have elevated levels of Neurogranin (48-76) in cerebrospinal fluid. |
| Synonyms | Neurogranin (48-76), mouse |
| Description | Neurogranin is a post synaptic protein that is expressed in dendritic cytoplasm. It modulates calcium-mediated signaling pathways and plays critical role in synaptic plasticity. Recently Neurogranin (48-76) was identified as a major neurogranin peptide fragment in human brain and it was found that patients with Alzheimer’s Disease have elevated levels of Neurogranin (48-76) in cerebrospinal fluid. |
| Sequence |
{Ser}{Gly}{Glu}{Cys}{Gly}{Arg}{Lys}{Gly}{Pro}{Gly}{Pro}{Gly} {Gly}{Pro}{Gly}{Gly}{Ala}{Gly}{Gly}{Ala}{Arg}{Gly}{Gly}{Ala} {Gly}{Gly}{Gly}{Pro}{Ser} |
| Sequence Shortening | SGECGRKGPGPGGPGGAGGARGGAGGGPS |
| Molecular Formula | C₉₁H₁₄₈N₃₆O₃₄S |
| Molecular Weight | 2322.46 |
| Length | 29 |
| Purity | >95% |
| Solubility | Soluble in Ultrapure water under 1mg/ml |
| Form | Lyophilized |
| Storage | Store at -20°C. Keep tightly closed. Store in a cool dry place. |